BDBM50082426 1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::1-(3-chlorophenyl)-3-(2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL137950

SMILES Clc1cccc(NC(=O)Nc2nc3nn(CCc4ccccc4)cc3c3nc(nn23)-c2ccco2)c1

InChI Key InChIKey=PARJXHXDPQTXJY-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50082426   

TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082426(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H...)
Affinity DataKi:  8nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082426(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 7.2-8.9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082426(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H...)
Affinity DataKi:  8nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082426(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H...)
Affinity DataKi:  13nMAssay Description:Displacement of [125]AB-MECA from human Adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082426(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H...)
Affinity DataKi:  13.3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082426(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H...)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed